The good news is that when you're applying for a more senior position, multiple relevant degrees and 10+ years of experience don't tend to be a problem, they tend to be an asset – if not a necessity. Your résumé and cover letter should alert a potential employer to the fact that you're looking for a management role, and foreground your education, experience, and transferrable skills relevant to that management role.
However, if you do want to apply for a lower level position, then the issue of "overqualified" may be relevant. In such a case, as mentioned in an Good luck in your job search.